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Flu vaccination linked to 40% reduced risk of Alzheimer?s disease
These are the films that Elvis Presley was about to interpret
Quantum network nodes with warm atoms
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                    [title] => Flu vaccination linked to 40% reduced risk of Alzheimer?s disease
                    [link] => https://coolnspicy.com/healthandscience/flu-vaccination-linked-to-40-reduced-risk-of-alzheimers-disease/
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                            [creator] => Tony Grantly
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                    [pubdate] => Sat, 25 Jun 2022 16:53:46 +0000
                    [category] => Health And ScienceAlzheimersdiseaseflulinkedreducedRiskvaccination
                    [guid] => https://coolnspicy.com/?p=24767
                    [description] => Journal Reference: Avram S. Bukhbinder, Yaobin Ling, Omar Hasan, Xiaoqian Jiang, Yejin Kim, Kamal N. Phelps, Rosemarie E. Schmandt, Albert Amran, Ryan Coburn, Srivathsan Ramesh, Qian Xiao, Paul E. Schulz. Risk of Alzheimer?s Disease Following Influenza Vaccination: A Claims-Based Cohort Study Using Propensity Score Matching. Journal of Alzheimer?s Disease, 2022; 1 DOI: 10.3233/JAD-220361 Research led ... Read more
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                        (
                            [encoded] => 

Journal Reference:

  1. Avram S. Bukhbinder, Yaobin Ling, Omar Hasan, Xiaoqian Jiang, Yejin Kim, Kamal N. Phelps, Rosemarie E. Schmandt, Albert Amran, Ryan Coburn, Srivathsan Ramesh, Qian Xiao, Paul E. Schulz. Risk of Alzheimer?s Disease Following Influenza Vaccination: A Claims-Based Cohort Study Using Propensity Score Matching. Journal of Alzheimer?s Disease, 2022; 1 DOI: 10.3233/JAD-220361

Research led by first author Avram S. Bukhbinder, MD, a recent alumnus of McGovern Medical School at UTHealth Houston, and senior author Paul. E. Schulz, MD, the Rick McCord Professor in Neurology at McGovern Medical School, compared the risk of Alzheimer?s disease incidence between patients with and without prior flu vaccination in a large nationwide sample of U.S. adults aged 65 and older.

An early online version of the paper detailing the findings is available in advance of its publication in the Aug. 2 issue of the Journal of Alzheimer?s Disease.

?We found that flu vaccination in older adults reduces the risk of developing Alzheimer?s disease for several years. The strength of this protective effect increased with the number of years that a person received an annual flu vaccine ? in other words, the rate of developing Alzheimer?s was lowest among those who consistently received the flu vaccine every year,? said Bukhbinder, who is still part of Schulz?s research team while in his first year of residency with the Division of Child Neurology at Massachusetts General Hospital. ?Future research should assess whether flu vaccination is also associated with the rate of symptom progression in patients who already have Alzheimer?s dementia.?

The study ? which comes two years after UTHealth Houston researchers found a possible link between the flu vaccine and reduced risk of Alzheimer?s disease ? analyzed a much larger sample than previous research, including 935,887 flu-vaccinated patients and 935,887 non-vaccinated patients.

During four-year follow-up appointments, about 5.1% of flu-vaccinated patients were found to have developed Alzheimer?s disease. Meanwhile, 8.5% of non-vaccinated patients had developed Alzheimer?s disease during follow-up.

These results underscore the strong protective effect of the flu vaccine against Alzheimer?s disease, according to Bukhbinder and Schulz. However, the underlying mechanisms behind this process require further study.

?Since there is evidence that several vaccines may protect from Alzheimer?s disease, we are thinking that it isn?t a specific effect of the flu vaccine,? said Schulz, who is also the Umphrey Family Professor in Neurodegenerative Diseases and director of the Neurocognitive Disorders Center at McGovern Medical School. ?Instead, we believe that the immune system is complex, and some alterations, such as pneumonia, may activate it in a way that makes Alzheimer?s disease worse. But other things that activate the immune system may do so in a different way ? one that protects from Alzheimer?s disease. Clearly, we have more to learn about how the immune system worsens or improves outcomes in this disease.?

Alzheimer?s disease affects more than 6 million people living in the U.S., with the number of affected individuals growing due to the nation?s aging population. Past studies have found a decreased risk of dementia associated with prior exposure to various adulthood vaccinations, including those for tetanus, polio, and herpes, in addition to the flu vaccine and others.

Additionally, as more time passes since the introduction of the COVID-19 vaccine and longer follow-up data becomes available, Bukhbinder said it will be worth investigating whether a similar association exists between COVID-19 vaccination and the risk of Alzheimer?s disease.

Co-authors from McGovern Medical School included Omar Hasan, research coordinator in the Department of Neurology and student at The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; Kamal N. Phelps, fourth-year medical student; Srivathsan Ramesh, PhD, first-year resident in the Department of Orthopedic Surgery; and alumni Albert Amran, MD, and Ryan Coburn, MD. Co-authors from UTHealth Houston School of Biomedical Informatics included Yaobin Ling, graduate research assistant; Xiaoqian Jiang, PhD, the Christopher Sarofim Family Professor in Biomedical Informatics and Engineering; and Yejin Kim, PhD, assistant professor. Qian Xiao, PhD, MPH, assistant professor in the Department of Epidemiology and Disease Control with UTHealth School of Public Health, also co-authored the study.

We would love to say thanks to the author of this short article for this outstanding material

Flu vaccination linked to 40% reduced risk of Alzheimer?s disease

) [summary] => Journal Reference: Avram S. Bukhbinder, Yaobin Ling, Omar Hasan, Xiaoqian Jiang, Yejin Kim, Kamal N. Phelps, Rosemarie E. Schmandt, Albert Amran, Ryan Coburn, Srivathsan Ramesh, Qian Xiao, Paul E. Schulz. Risk of Alzheimer?s Disease Following Influenza Vaccination: A Claims-Based Cohort Study Using Propensity Score Matching. Journal of Alzheimer?s Disease, 2022; 1 DOI: 10.3233/JAD-220361 Research led ... Read more [atom_content] =>

Journal Reference:

  1. Avram S. Bukhbinder, Yaobin Ling, Omar Hasan, Xiaoqian Jiang, Yejin Kim, Kamal N. Phelps, Rosemarie E. Schmandt, Albert Amran, Ryan Coburn, Srivathsan Ramesh, Qian Xiao, Paul E. Schulz. Risk of Alzheimer?s Disease Following Influenza Vaccination: A Claims-Based Cohort Study Using Propensity Score Matching. Journal of Alzheimer?s Disease, 2022; 1 DOI: 10.3233/JAD-220361

Research led by first author Avram S. Bukhbinder, MD, a recent alumnus of McGovern Medical School at UTHealth Houston, and senior author Paul. E. Schulz, MD, the Rick McCord Professor in Neurology at McGovern Medical School, compared the risk of Alzheimer?s disease incidence between patients with and without prior flu vaccination in a large nationwide sample of U.S. adults aged 65 and older.

An early online version of the paper detailing the findings is available in advance of its publication in the Aug. 2 issue of the Journal of Alzheimer?s Disease.

?We found that flu vaccination in older adults reduces the risk of developing Alzheimer?s disease for several years. The strength of this protective effect increased with the number of years that a person received an annual flu vaccine ? in other words, the rate of developing Alzheimer?s was lowest among those who consistently received the flu vaccine every year,? said Bukhbinder, who is still part of Schulz?s research team while in his first year of residency with the Division of Child Neurology at Massachusetts General Hospital. ?Future research should assess whether flu vaccination is also associated with the rate of symptom progression in patients who already have Alzheimer?s dementia.?

The study ? which comes two years after UTHealth Houston researchers found a possible link between the flu vaccine and reduced risk of Alzheimer?s disease ? analyzed a much larger sample than previous research, including 935,887 flu-vaccinated patients and 935,887 non-vaccinated patients.

During four-year follow-up appointments, about 5.1% of flu-vaccinated patients were found to have developed Alzheimer?s disease. Meanwhile, 8.5% of non-vaccinated patients had developed Alzheimer?s disease during follow-up.

These results underscore the strong protective effect of the flu vaccine against Alzheimer?s disease, according to Bukhbinder and Schulz. However, the underlying mechanisms behind this process require further study.

?Since there is evidence that several vaccines may protect from Alzheimer?s disease, we are thinking that it isn?t a specific effect of the flu vaccine,? said Schulz, who is also the Umphrey Family Professor in Neurodegenerative Diseases and director of the Neurocognitive Disorders Center at McGovern Medical School. ?Instead, we believe that the immune system is complex, and some alterations, such as pneumonia, may activate it in a way that makes Alzheimer?s disease worse. But other things that activate the immune system may do so in a different way ? one that protects from Alzheimer?s disease. Clearly, we have more to learn about how the immune system worsens or improves outcomes in this disease.?

Alzheimer?s disease affects more than 6 million people living in the U.S., with the number of affected individuals growing due to the nation?s aging population. Past studies have found a decreased risk of dementia associated with prior exposure to various adulthood vaccinations, including those for tetanus, polio, and herpes, in addition to the flu vaccine and others.

Additionally, as more time passes since the introduction of the COVID-19 vaccine and longer follow-up data becomes available, Bukhbinder said it will be worth investigating whether a similar association exists between COVID-19 vaccination and the risk of Alzheimer?s disease.

Co-authors from McGovern Medical School included Omar Hasan, research coordinator in the Department of Neurology and student at The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; Kamal N. Phelps, fourth-year medical student; Srivathsan Ramesh, PhD, first-year resident in the Department of Orthopedic Surgery; and alumni Albert Amran, MD, and Ryan Coburn, MD. Co-authors from UTHealth Houston School of Biomedical Informatics included Yaobin Ling, graduate research assistant; Xiaoqian Jiang, PhD, the Christopher Sarofim Family Professor in Biomedical Informatics and Engineering; and Yejin Kim, PhD, assistant professor. Qian Xiao, PhD, MPH, assistant professor in the Department of Epidemiology and Disease Control with UTHealth School of Public Health, also co-authored the study.

We would love to say thanks to the author of this short article for this outstanding material

Flu vaccination linked to 40% reduced risk of Alzheimer?s disease

[date_timestamp] => 1656176026 ) [1] => Array ( [title] => These are the films that Elvis Presley was about to interpret [link] => https://coolnspicy.com/celebrity/these-are-the-films-that-elvis-presley-was-about-to-interpret/ [dc] => Array ( [creator] => Sally Scully ) [pubdate] => Sat, 25 Jun 2022 16:16:06 +0000 [category] => CelebrityElvisFilmsinterpretPresley [guid] => https://coolnspicy.com/?p=24755 [description] => From Midnight Cowboy to West Side Story to The Godfather it would have been a lot different if “King of Rock and Roll” manager Colonel Tom Parker hadn’t turned down so many roles on his behalf. What are the movies that Elvis almost acted in? For more than 30 years, Elvis Aaron Presley was one ... Read more [content] => Array ( [encoded] =>

From Midnight Cowboy to West Side Story to The Godfather it would have been a lot different if “King of Rock and Roll” manager Colonel Tom Parker hadn’t turned down so many roles on his behalf.

What are the movies that Elvis almost acted in?

For more than 30 years, Elvis Aaron Presley was one of the most quoted faces in Hollywood. From its inception the “Rey” he dominated the charts with his music as well as television, thanks to his appearances on variety shows.

Nevertheless, One of Elvis’s strengths was acting, with classics like “In The Ghetto” (1958), “Blue Hawaii” (1961), or “Girls! Girls! Girls!” where he ended up becoming an idol for the youth of his time.

Presley’s ambitions over Hollywood were frequently lost by his manager, Colonel Tom Parker. And it is that the story of Elvis on the big screen would have been very different without the influence of the colonel. It is worth mentioning that in the new film about the “Rey del Rock and Roll” there is a key scene that shows how difficult it was for Presley to turn down roles.

According to the Baz Luhrmann biopic “Elvis” a repentant Elvis (Austin Butler) is shown explaining that he will not be able to co-star with Barbara Streisand in the remake of A Star Is Born (1976) because negotiations between Streisand and Parker ( Tom Hanks) did not end well.

Getty Images

Thunder Road (1958)

Robert Mitchum had seen Presley on stage before he was famous. What’s more, after Elvis came to Hollywood they became friends.

During a Christmas party, while playing songs together, Mitchum tried to convince Presley to take on the role of his younger brother in Thunder Road, a booze-fueled chase thriller he was producing.

Parker, however, balked at the idea as it was not a musical. And he pointed out that he didn’t want Elvis “to make a movie that he couldn’t get an album out of.”. The role of Robin Doolan that the “King” had been offered eventually went to Mitchum’s son, James Mitchum.

Cat on a Hot Tin Roof (1958)

In the same film as “Thunder Road,” Elvis was also offered the role of Brick Pollitt in the adaptation of Tennessee Williams’ play about an alcoholic former high school jock trying to recapture his glory days. And who resists the affection of his wife, Maggie, better known as the cat, played by Elizabeth Taylor.

The colonel turned down the role on behalf of Elvis and Paul Newman was cast instead.

The Defiant Ones (1958)

Although by 1958 Elvis had turned down quite a few roles, had also made his first three films; Love Me Tender, Loving You and the hit Jailhouse Rock. So to date, his film career was already established. Nevertheless, the singer was eager to play John “Joker” Jackson opposite Sidney Poitier in “The Defiant Ones.”

As was customary, the colonel did not accept the role. And finally John “Joker” Jackson was played by Tony Curtis. “The Defiant Ones” was nominated for Best Picture and Curtis for Best Actor.

West Side Story (1961)

Elvis could have been the famous Tony from “West Side Story”. For a long time it was rumored that Presley was considered for the leading role in this film. But as usual, Parker turned down the role as he thought a street gang movie was not good for Elvis’s image.

Sweet Bird of Youth (1962)

The Colonel had rejected “Thunder Road” in 1958. And this new Tennessee Williams movie would be no exception.. This time Elvis was called to play Chance Wayne, a homeless man who has a relationship with a movie star.

Parker again turned Williams down, this time on the grounds that he didn’t want Elvis to play a sleazy character. Finally the role was taken again by Paul Newman.

The Godfather (1972)

Elvis Presley was a great admirer of the novel by Mario Puzo and wanted to play the role of consigliere Tom Hagen. Role that finally fell to Robert Duvall. Many sources point out that the process with Presley went so far that he was asked to do a screen test. And also that he lobbied for the lead role.



We want to give thanks to the writer of this post for this incredible content

These are the films that Elvis Presley was about to interpret

) [summary] => From Midnight Cowboy to West Side Story to The Godfather it would have been a lot different if “King of Rock and Roll” manager Colonel Tom Parker hadn’t turned down so many roles on his behalf. What are the movies that Elvis almost acted in? For more than 30 years, Elvis Aaron Presley was one ... Read more [atom_content] =>

From Midnight Cowboy to West Side Story to The Godfather it would have been a lot different if “King of Rock and Roll” manager Colonel Tom Parker hadn’t turned down so many roles on his behalf.

What are the movies that Elvis almost acted in?

For more than 30 years, Elvis Aaron Presley was one of the most quoted faces in Hollywood. From its inception the “Rey” he dominated the charts with his music as well as television, thanks to his appearances on variety shows.

Nevertheless, One of Elvis’s strengths was acting, with classics like “In The Ghetto” (1958), “Blue Hawaii” (1961), or “Girls! Girls! Girls!” where he ended up becoming an idol for the youth of his time.

Presley’s ambitions over Hollywood were frequently lost by his manager, Colonel Tom Parker. And it is that the story of Elvis on the big screen would have been very different without the influence of the colonel. It is worth mentioning that in the new film about the “Rey del Rock and Roll” there is a key scene that shows how difficult it was for Presley to turn down roles.

According to the Baz Luhrmann biopic “Elvis” a repentant Elvis (Austin Butler) is shown explaining that he will not be able to co-star with Barbara Streisand in the remake of A Star Is Born (1976) because negotiations between Streisand and Parker ( Tom Hanks) did not end well.

Getty Images

Thunder Road (1958)

Robert Mitchum had seen Presley on stage before he was famous. What’s more, after Elvis came to Hollywood they became friends.

During a Christmas party, while playing songs together, Mitchum tried to convince Presley to take on the role of his younger brother in Thunder Road, a booze-fueled chase thriller he was producing.

Parker, however, balked at the idea as it was not a musical. And he pointed out that he didn’t want Elvis “to make a movie that he couldn’t get an album out of.”. The role of Robin Doolan that the “King” had been offered eventually went to Mitchum’s son, James Mitchum.

Cat on a Hot Tin Roof (1958)

In the same film as “Thunder Road,” Elvis was also offered the role of Brick Pollitt in the adaptation of Tennessee Williams’ play about an alcoholic former high school jock trying to recapture his glory days. And who resists the affection of his wife, Maggie, better known as the cat, played by Elizabeth Taylor.

The colonel turned down the role on behalf of Elvis and Paul Newman was cast instead.

The Defiant Ones (1958)

Although by 1958 Elvis had turned down quite a few roles, had also made his first three films; Love Me Tender, Loving You and the hit Jailhouse Rock. So to date, his film career was already established. Nevertheless, the singer was eager to play John “Joker” Jackson opposite Sidney Poitier in “The Defiant Ones.”

As was customary, the colonel did not accept the role. And finally John “Joker” Jackson was played by Tony Curtis. “The Defiant Ones” was nominated for Best Picture and Curtis for Best Actor.

West Side Story (1961)

Elvis could have been the famous Tony from “West Side Story”. For a long time it was rumored that Presley was considered for the leading role in this film. But as usual, Parker turned down the role as he thought a street gang movie was not good for Elvis’s image.

Sweet Bird of Youth (1962)

The Colonel had rejected “Thunder Road” in 1958. And this new Tennessee Williams movie would be no exception.. This time Elvis was called to play Chance Wayne, a homeless man who has a relationship with a movie star.

Parker again turned Williams down, this time on the grounds that he didn’t want Elvis to play a sleazy character. Finally the role was taken again by Paul Newman.

The Godfather (1972)

Elvis Presley was a great admirer of the novel by Mario Puzo and wanted to play the role of consigliere Tom Hagen. Role that finally fell to Robert Duvall. Many sources point out that the process with Presley went so far that he was asked to do a screen test. And also that he lobbied for the lead role.



We want to give thanks to the writer of this post for this incredible content

These are the films that Elvis Presley was about to interpret

[date_timestamp] => 1656173766 ) [2] => Array ( [title] => Quantum network nodes with warm atoms [link] => https://coolnspicy.com/healthandscience/quantum-network-nodes-with-warm-atoms/ [dc] => Array ( [creator] => Tony Grantly ) [pubdate] => Sat, 25 Jun 2022 15:37:05 +0000 [category] => Health And ScienceatomsnetworknodesquantumWarm [guid] => https://coolnspicy.com/?p=24750 [description] => Journal Reference: Gianni Buser, Roberto Mottola, Björn Cotting, Janik Wolters, Philipp Treutlein. Single-Photon Storage in a Ground-State Vapor Cell Quantum Memory. PRX Quantum, 2022; 3 (2) DOI: 10.1103/PRXQuantum.3.020349 In quantum communication networks, information is transmitted by single particles of light (photons). At the nodes of such a network buffer elements are needed which can temporarily ... Read more [content] => Array ( [encoded] =>

Journal Reference:

  1. Gianni Buser, Roberto Mottola, Björn Cotting, Janik Wolters, Philipp Treutlein. Single-Photon Storage in a Ground-State Vapor Cell Quantum Memory. PRX Quantum, 2022; 3 (2) DOI: 10.1103/PRXQuantum.3.020349

In quantum communication networks, information is transmitted by single particles of light (photons). At the nodes of such a network buffer elements are needed which can temporarily store, and later re-emit, the quantum information contained in the photons.

Researchers at the University of Basel in the group of Prof. Philipp Treutlein have now developed a quantum memory that is based on an atomic gas inside a glass cell. The atoms do not have to be specially cooled, which makes the memory easy to produce and versatile, even for satellite applications. Moreover, the researchers have realized a single photon source which allowed them to test the quality and storage time of the quantum memory. Their results were recently published in the scientific journal PRX Quantum.

Warm atoms in vapor cells

?The suitability of warm atoms in vapor cells for quantum memories has been investigated for the past twenty years,? says Gianni Buser, who worked on the experiment as a PhD student. ?Usually, however, attenuated laser beams ? and hence classical light ? were used.? In classical light, the number of photons hitting the vapor cell in a certain period follows a statistical distribution; on average it is one photon, but sometimes it can be two, three or none.

To test the quantum memory with ?quantum light? ? that is, always precisely one photon ? Treutlein and his co-workers developed a dedicated single photon source that emits exactly one photon at a time. The instant when that happens is heralded by a second photon, which is always sent out simultaneously with the first one. This allows the quantum memory to be activated at the right moment.

The single photon is then directed into the quantum memory where, with the help of a control laser beam, the photon causes more than a billion rubidium atoms to take on a so-called superposition state of two possible energy levels of the atoms. The photon itself vanishes in the process, but the information contained in it is transformed into the superposition state of the atoms. A brief pulse of the control laser can then read out that information after a certain storage time and transform it back into a photon.

Reducing read-out noise

?Up to now, a critical point has been noise ? additional light that is produced during the read-out and that can compromise the quality of the photon,? explains Roberto Mottola, another PhD student in Treutlein?s lab. Using a few tricks, the physicists were able to reduce that noise sufficiently so that after storage times of several hundred nanoseconds the single photon quality was still high.

?Those storage times are not very long, and we didn?t actually optimize them for this study,? Treutlein says, ?but already now they are more than a hundred times longer than the duration of the stored single photon pulse.? This means that the quantum memory developed by the Basel researchers can already be employed for interesting applications. For instance, it can synchronize randomly produced single photons, which can then be used in various quantum information applications.

We wish to thank the author of this write-up for this outstanding material

Quantum network nodes with warm atoms

) [summary] => Journal Reference: Gianni Buser, Roberto Mottola, Björn Cotting, Janik Wolters, Philipp Treutlein. Single-Photon Storage in a Ground-State Vapor Cell Quantum Memory. PRX Quantum, 2022; 3 (2) DOI: 10.1103/PRXQuantum.3.020349 In quantum communication networks, information is transmitted by single particles of light (photons). At the nodes of such a network buffer elements are needed which can temporarily ... Read more [atom_content] =>

Journal Reference:

  1. Gianni Buser, Roberto Mottola, Björn Cotting, Janik Wolters, Philipp Treutlein. Single-Photon Storage in a Ground-State Vapor Cell Quantum Memory. PRX Quantum, 2022; 3 (2) DOI: 10.1103/PRXQuantum.3.020349

In quantum communication networks, information is transmitted by single particles of light (photons). At the nodes of such a network buffer elements are needed which can temporarily store, and later re-emit, the quantum information contained in the photons.

Researchers at the University of Basel in the group of Prof. Philipp Treutlein have now developed a quantum memory that is based on an atomic gas inside a glass cell. The atoms do not have to be specially cooled, which makes the memory easy to produce and versatile, even for satellite applications. Moreover, the researchers have realized a single photon source which allowed them to test the quality and storage time of the quantum memory. Their results were recently published in the scientific journal PRX Quantum.

Warm atoms in vapor cells

?The suitability of warm atoms in vapor cells for quantum memories has been investigated for the past twenty years,? says Gianni Buser, who worked on the experiment as a PhD student. ?Usually, however, attenuated laser beams ? and hence classical light ? were used.? In classical light, the number of photons hitting the vapor cell in a certain period follows a statistical distribution; on average it is one photon, but sometimes it can be two, three or none.

To test the quantum memory with ?quantum light? ? that is, always precisely one photon ? Treutlein and his co-workers developed a dedicated single photon source that emits exactly one photon at a time. The instant when that happens is heralded by a second photon, which is always sent out simultaneously with the first one. This allows the quantum memory to be activated at the right moment.

The single photon is then directed into the quantum memory where, with the help of a control laser beam, the photon causes more than a billion rubidium atoms to take on a so-called superposition state of two possible energy levels of the atoms. The photon itself vanishes in the process, but the information contained in it is transformed into the superposition state of the atoms. A brief pulse of the control laser can then read out that information after a certain storage time and transform it back into a photon.

Reducing read-out noise

?Up to now, a critical point has been noise ? additional light that is produced during the read-out and that can compromise the quality of the photon,? explains Roberto Mottola, another PhD student in Treutlein?s lab. Using a few tricks, the physicists were able to reduce that noise sufficiently so that after storage times of several hundred nanoseconds the single photon quality was still high.

?Those storage times are not very long, and we didn?t actually optimize them for this study,? Treutlein says, ?but already now they are more than a hundred times longer than the duration of the stored single photon pulse.? This means that the quantum memory developed by the Basel researchers can already be employed for interesting applications. For instance, it can synchronize randomly produced single photons, which can then be used in various quantum information applications.

We wish to thank the author of this write-up for this outstanding material

Quantum network nodes with warm atoms

[date_timestamp] => 1656171425 ) [3] => Array ( [title] => My three year old daughter falls asleep very late! Tips and tricks to help you fall asleep ? COOL PARENTS MAKE HAPPY KIDS [link] => https://coolnspicy.com/magazine/my-three-year-old-daughter-falls-asleep-very-late-tips-and-tricks-to-help-you-fall-asleep-cool-parents-make-happy-kids/ [dc] => Array ( [creator] => Pauline Moonlky ) [pubdate] => Sat, 25 Jun 2022 15:13:02 +0000 [category] => MagazineasleepcooldaughterFallfallsHappyKidslateParentsTipstricks [guid] => https://coolnspicy.com/?p=24744 [description] => ?My daughter has trouble falling asleep?, ?my four-year-old child falls asleep very late?, ?my son can only fall asleep with me, and not before 10-11 pm?? A child who sleeping late, getting up 50 times a night, calling their parents 20-30-60 times (yes, yes ?), it can be exhausting. And the more we are tired, ... Read more [content] => Array ( [encoded] =>

?My daughter has trouble falling asleep?, ?my four-year-old child falls asleep very late?, ?my son can only fall asleep with me, and not before 10-11 pm?? A child who sleeping late, getting up 50 times a night, calling their parents 20-30-60 times (yes, yes ?), it can be exhausting.

And the more we are tired, the less patient we are!

However, if each child can have his rhythm, it is important not to consider problems around sleep and falling asleep as inevitable. A child of 2, 3, 4 years old, who is mentally well, is normally able to fall asleep alone, after having had a great time with his or her parents. It can of course happen that some days are more complicated than others, hazards are part of life, but on the other hand life should not become a hazard.. It remains to find the ritual or the rules that will allow him to serenely join the arm of Morpheus.

Here is a small collection of tips in addition to the discussion thread of the CPMHK forum.

Why does a child have trouble falling asleep?

The first thing you can do is try to understand the reason for difficulty falling asleep.

Rhythm problem?

Around 2-3 years old, the child needs less sleep, and sometimes he no longer needs a nap, or not as long a nap, or less close to bedtime. Playing on the siesta, testing, can be a solution.

A lack of ?his dose of parent??

Another classic factor: the child frustrated at having benefited little from his parent has difficulty going to bed, and therefore leaving it. And there, it is the quality of the time shared together that takes precedence over the quantity. Plan 15, 20, 30 minutes, or 1 hour of connection with him in the evening, of play, or sharing, where you are 100% with him then makes things a lot easier.

Disruptive events?

We are often amazed to see the silent connection that there is between a child and his parents. It sometimes happens that we have lived a difficult time during pregnancy or the first years of our child’s life (mourning, breakup, job loss, etc.), plays on the child’s sleep, if it has been complicated since birth. In order not to worry him and because he cannot necessarily understand, we did not talk to him about it. And yet, it is possible that he felt it and that it disturbed him. Without understanding why, he is anxious and therefore finds it difficult to leave us, making the separation from bedtime difficult.

In this case, it may be interesting to put simple words on it: ?You know, when you were in my belly, a person who I love very much passed away and I was very sad. Now it’s better, but you don’t have to worry about me!?

And then sometimes, it’s simply the lack of rules that complicates bedtime.

Tips and advice from parents to help a child who falls asleep very late

When we have tried explanations, threats, firmness, the reward-punishment combo, gentleness, listening and understanding, we no longer really know what we can do. Here are your tips and advice.

Trust that our child can fall asleep on their own

Easier said than done ! For Aurelie ?If we are not sure that our child will fall asleep, if we are already tense at the idea that he will call us back several times, there is a good chance that this will happen!? Indeed, a child feels the trust of his parent, and unconsciously our doubt in his ability to sleep becomes his doubt. (Well yes, that would be too simple ?!)

Empower the child

For Margot, whose 3.5-year-old son used to call several times before bedtime, the solution was to leave the night light on for a few minutes (on timer) while her son looked at his books calmly except for the lights. This empowerment and quiet alone time allowed her son to fall asleep without needing his parents next to him.

Lay down a clear rule

Aurélie’s 4-year-old daughter fell asleep every night between 10 and 11 p.m. She decided to set up a timer on the phone by involving her: “We’re going to put in a new rule honey. We will choose a music together. At the end of the music, when the phone rings, I will come and turn off the light and you can fall asleep peacefully.?

The fact of it formulate as a rule allowed the child to take it seriously, especially since Aurélie had to be convinced of this solution in her attitude. And little by little, she moved the bedtime forward a few minutes.

Make joker cards

Cecile’s solution was to make three pretty joker cards that her 3 year old daughter can use. She therefore has the possibility of calling her back three times after which, mum or dad will no longer come back to the room. The firmness and simplicity of this rule helped the little girl to fall asleep more peacefully and not to call her parents 50 times.

Leave a trace of the parents in the room

Faced with a child who absolutely wants to fall asleep systematically with his mother or father, the solution may have been to set up a picture frame close to the child. A bit like an extension of the parent, the certainty that mom or dad are always watching over him.

It can also be a cuddly toy or item of clothing with the parent’s scent (my daughter used one of my worn T-shirts and stuck her nose in the hollow of the armpit ?).

Can also invest an object of all the love of the parent: for example a small stone (which can be chosen according to the lithotherapy, but it can also be a nice holiday souvenir), a bracelet, or even a glitter spray to put on the pillow . We can explain to the child that this object contains our love, our confidence, our serenity and that it will give him all the calm necessary to fall asleep.

Condition

At bedtime, the important thing is to increase the level of melatonin, the sleep hormone. This is the whole purpose of bedtime ritual : decreasing light, decrescendo activity, possibly a small relaxing bath? Some parents precede bedtime with a small massage. Thus, Aurore began massaging her son’s feet around the age of 2 and a half by stimulating specific plantar reflexology points. And that helps calm him down. Find more tips in our article on different ways to put a child to sleep et put an end to the big difficulties of bedtime.

We have also gathered many other valuable tips in our SUPER SLEEP PACK » with all the tips to end bedtime difficulties? Enter your email below to receive it for free in your mailbox

An outside boost can help you (quickly)

When we’ve tried everything and before the breaking point (yes, the burn-out parental, it exists!), external help is sometimes life-saving. It can be physical, physiological or psychological? or even a bit of all of that!

  • Le coaching ?He is finally sleeping (and so are we)? by CPMHK : thousands of parents have already followed it and testify that this coaching has ?saved their family life?. Charlotte Ducharme, and her whole team of super sleep expert psychologist-coaches, will accompany you, hand in hand for 15 days until your family (finally) returns to a normal life.
  • Hypnosis: in the forum, Aline used hypnosis, which helped her extremely anxious daughter find her way back to peaceful sleep. And yet, it had been more than 12 years that the difficulties had been installed. The sophrology perhaps valuable help.
  • Not always well known, but incredibly present, problems with falling asleep or anxiety can be linked to poor integration of archaic reflexes.
  • Other parents testify to the success encountered with different techniques such as microkiné, osteopathy, homeopathy or the diffusion of essential oils like lavender to relax and help you fall asleep (respecting the rules of use of course).

So what do we do with a child who falls asleep too late?

Remember, sleep disorders are not inevitable…

However, what is certain is that a child who falls asleep very late, who does not want to go to bed alone, is exhausting for the child, as for his family.

When you feel like you’ve tried everything, it’s better to turn to outside help that can help you overcome sleep problems. Good luck and above all, don’t be alone!

We wish to give thanks to the author of this short article for this amazing web content

My three year old daughter falls asleep very late! Tips and tricks to help you fall asleep – COOL PARENTS MAKE HAPPY KIDS

) [summary] => ?My daughter has trouble falling asleep?, ?my four-year-old child falls asleep very late?, ?my son can only fall asleep with me, and not before 10-11 pm?? A child who sleeping late, getting up 50 times a night, calling their parents 20-30-60 times (yes, yes ?), it can be exhausting. And the more we are tired, ... Read more [atom_content] =>

?My daughter has trouble falling asleep?, ?my four-year-old child falls asleep very late?, ?my son can only fall asleep with me, and not before 10-11 pm?? A child who sleeping late, getting up 50 times a night, calling their parents 20-30-60 times (yes, yes ?), it can be exhausting.

And the more we are tired, the less patient we are!

However, if each child can have his rhythm, it is important not to consider problems around sleep and falling asleep as inevitable. A child of 2, 3, 4 years old, who is mentally well, is normally able to fall asleep alone, after having had a great time with his or her parents. It can of course happen that some days are more complicated than others, hazards are part of life, but on the other hand life should not become a hazard.. It remains to find the ritual or the rules that will allow him to serenely join the arm of Morpheus.

Here is a small collection of tips in addition to the discussion thread of the CPMHK forum.

Why does a child have trouble falling asleep?

The first thing you can do is try to understand the reason for difficulty falling asleep.

Rhythm problem?

Around 2-3 years old, the child needs less sleep, and sometimes he no longer needs a nap, or not as long a nap, or less close to bedtime. Playing on the siesta, testing, can be a solution.

A lack of ?his dose of parent??

Another classic factor: the child frustrated at having benefited little from his parent has difficulty going to bed, and therefore leaving it. And there, it is the quality of the time shared together that takes precedence over the quantity. Plan 15, 20, 30 minutes, or 1 hour of connection with him in the evening, of play, or sharing, where you are 100% with him then makes things a lot easier.

Disruptive events?

We are often amazed to see the silent connection that there is between a child and his parents. It sometimes happens that we have lived a difficult time during pregnancy or the first years of our child’s life (mourning, breakup, job loss, etc.), plays on the child’s sleep, if it has been complicated since birth. In order not to worry him and because he cannot necessarily understand, we did not talk to him about it. And yet, it is possible that he felt it and that it disturbed him. Without understanding why, he is anxious and therefore finds it difficult to leave us, making the separation from bedtime difficult.

In this case, it may be interesting to put simple words on it: ?You know, when you were in my belly, a person who I love very much passed away and I was very sad. Now it’s better, but you don’t have to worry about me!?

And then sometimes, it’s simply the lack of rules that complicates bedtime.

Tips and advice from parents to help a child who falls asleep very late

When we have tried explanations, threats, firmness, the reward-punishment combo, gentleness, listening and understanding, we no longer really know what we can do. Here are your tips and advice.

Trust that our child can fall asleep on their own

Easier said than done ! For Aurelie ?If we are not sure that our child will fall asleep, if we are already tense at the idea that he will call us back several times, there is a good chance that this will happen!? Indeed, a child feels the trust of his parent, and unconsciously our doubt in his ability to sleep becomes his doubt. (Well yes, that would be too simple ?!)

Empower the child

For Margot, whose 3.5-year-old son used to call several times before bedtime, the solution was to leave the night light on for a few minutes (on timer) while her son looked at his books calmly except for the lights. This empowerment and quiet alone time allowed her son to fall asleep without needing his parents next to him.

Lay down a clear rule

Aurélie’s 4-year-old daughter fell asleep every night between 10 and 11 p.m. She decided to set up a timer on the phone by involving her: “We’re going to put in a new rule honey. We will choose a music together. At the end of the music, when the phone rings, I will come and turn off the light and you can fall asleep peacefully.?

The fact of it formulate as a rule allowed the child to take it seriously, especially since Aurélie had to be convinced of this solution in her attitude. And little by little, she moved the bedtime forward a few minutes.

Make joker cards

Cecile’s solution was to make three pretty joker cards that her 3 year old daughter can use. She therefore has the possibility of calling her back three times after which, mum or dad will no longer come back to the room. The firmness and simplicity of this rule helped the little girl to fall asleep more peacefully and not to call her parents 50 times.

Leave a trace of the parents in the room

Faced with a child who absolutely wants to fall asleep systematically with his mother or father, the solution may have been to set up a picture frame close to the child. A bit like an extension of the parent, the certainty that mom or dad are always watching over him.

It can also be a cuddly toy or item of clothing with the parent’s scent (my daughter used one of my worn T-shirts and stuck her nose in the hollow of the armpit ?).

Can also invest an object of all the love of the parent: for example a small stone (which can be chosen according to the lithotherapy, but it can also be a nice holiday souvenir), a bracelet, or even a glitter spray to put on the pillow . We can explain to the child that this object contains our love, our confidence, our serenity and that it will give him all the calm necessary to fall asleep.

Condition

At bedtime, the important thing is to increase the level of melatonin, the sleep hormone. This is the whole purpose of bedtime ritual : decreasing light, decrescendo activity, possibly a small relaxing bath? Some parents precede bedtime with a small massage. Thus, Aurore began massaging her son’s feet around the age of 2 and a half by stimulating specific plantar reflexology points. And that helps calm him down. Find more tips in our article on different ways to put a child to sleep et put an end to the big difficulties of bedtime.

We have also gathered many other valuable tips in our SUPER SLEEP PACK » with all the tips to end bedtime difficulties? Enter your email below to receive it for free in your mailbox

An outside boost can help you (quickly)

When we’ve tried everything and before the breaking point (yes, the burn-out parental, it exists!), external help is sometimes life-saving. It can be physical, physiological or psychological? or even a bit of all of that!

  • Le coaching ?He is finally sleeping (and so are we)? by CPMHK : thousands of parents have already followed it and testify that this coaching has ?saved their family life?. Charlotte Ducharme, and her whole team of super sleep expert psychologist-coaches, will accompany you, hand in hand for 15 days until your family (finally) returns to a normal life.
  • Hypnosis: in the forum, Aline used hypnosis, which helped her extremely anxious daughter find her way back to peaceful sleep. And yet, it had been more than 12 years that the difficulties had been installed. The sophrology perhaps valuable help.
  • Not always well known, but incredibly present, problems with falling asleep or anxiety can be linked to poor integration of archaic reflexes.
  • Other parents testify to the success encountered with different techniques such as microkiné, osteopathy, homeopathy or the diffusion of essential oils like lavender to relax and help you fall asleep (respecting the rules of use of course).

So what do we do with a child who falls asleep too late?

Remember, sleep disorders are not inevitable…

However, what is certain is that a child who falls asleep very late, who does not want to go to bed alone, is exhausting for the child, as for his family.

When you feel like you’ve tried everything, it’s better to turn to outside help that can help you overcome sleep problems. Good luck and above all, don’t be alone!

We wish to give thanks to the author of this short article for this amazing web content

My three year old daughter falls asleep very late! Tips and tricks to help you fall asleep – COOL PARENTS MAKE HAPPY KIDS

[date_timestamp] => 1656169982 ) [4] => Array ( [title] => Far Sector, NK Jemisin and Jamal Campbell?s Green Lantern Noir ? Danger Room [link] => https://coolnspicy.com/influential-people/far-sector-nk-jemisin-and-jamal-campbells-green-lantern-noir-danger-room/ [dc] => Array ( [creator] => Harold Kent ) [pubdate] => Sat, 25 Jun 2022 15:11:03 +0000 [category] => Influential PeopleCampbellsdangerGreenJamalJemisinLanternnoirsector [guid] => https://coolnspicy.com/?p=24738 [description] => ECC recovers in this compilation volume the twelve issues that were originally published of this story that can be read by itself, or understood as the origin of a new Green Lantern. In recent years, the superhero comics that have gone the furthest are those that not only go a little out of the norm ... Read more [content] => Array ( [encoded] =>

ECC recovers in this compilation volume the twelve issues that were originally published of this story that can be read by itself, or understood as the origin of a new Green Lantern.

In recent years, the superhero comics that have gone the furthest are those that not only go a little out of the norm but have also been able to include current themes in their development from a prism that makes readers think. And it is that At this point in the story, and taking into account everything that is published each month, better content is increasingly demanded on the pages we read.. And in the specific case of DCwhich has been messing around quite a bit for a few years in terms of administrative decisions, is noticeable for good when they let their authors develop their stories without pressure.

In case of Far Sectorpublished in Spanish by ECC in a single volume, it is quite curious. This story of twelve issues in total appears under the seal DC?s Young Animalco-created by Gerard Way. Yes, the singer and songwriter of My Chemical Romance, who is also a comic book writer and editor. This stamp aims to relaunch characters and stories within the universe DCbut focusing on a more adult age group. Way wanted to create a new version of Green Lantern, in a very special direction, and for this he decided to hire NK Jemisina well-known and award-winning novelist. And she said yes. Together with the very detailed graphic section of Jamal Campbell pops up Far Sectorthe dream of Way came true.

The story of Far Sector it starts with a murder in the Enduring City. The first in five hundred years. The problem? That world has spent generations without suffering any kind of violent death thanks to the control of emotions that the government imposed some time ago. And that means they are not prepared to investigate what has happened. Luckily, the green lanterns are there to protect all corners of space, including that, the furthest sector of planet Earth. Sojourner “Jo” Mullein is still getting used to it to live in a sector where she is the only one who has feelings, where food is more than dangerous for her if she is not careful and where bureaucracy is as tedious as anywhere else. Not counting your adaptation to Green Lantern’s post. Therefore, that first murder will fall into his human hands, with all that this entails.

SectorLejano01

To this must be added that it is the only human, since that sector is inhabited by three species that coexist thanks to the aforementioned control of emotions. If there is no anger, sadness, fear… but no sympathy, love or joy, it seems that as a society it should be quite a walk. However, Mullein has begun to see strange things, emotionally active beings thanks to a new drug that inhibits the control of emotions. In order to save the population of the sector, Mullein must first overcome his past to face his present and thus protect the sector from him.

With these parameters NK Jemisin create a round story where your Green Lantern eShe’s more of an investigator than a conventional superhero. With the perfect mix between noir and science fictionthe script of Jemisin It focuses on the representation of very current problems such as racism, changing races for alien species, abuse of power, hatred and disinformation as political propaganda, among others that we will not specify here so as not to destroy part of the story. Don’t miss out on the action that is expected in this type of comics, and includes battle scenes and development of powers of the protagonist. However, it does so with a procedural narrative typical of the detective genre. Its narrative is quite linear, with a couple of time jumps, in the form of memories, to give more meaning to the story of the protagonist.

SectorLejano02

Jamal Campbell’s graphic sectionwho not only takes care of the drawing but also the color, it is very effective. Striking both in its designs and its colors. With incredible detail in the expressions of the protagonist, and some character designs of the rest of the species that, at times, makes it difficult to think that they are not feeling anything. Sometimes this happens because of the script, but sometimes it’s because the art of Campbell fills them with life. But she doesn’t bother at all, quite the opposite. Furthermore, the edition of ECC It has a section of sketches and character designs in which you can see the use of each of them during the volume. The graphic solutions for the development of the story are quite conventional, including the battles, but both the script and the graphic section make this irrelevant. They do not need large displays for readers to enjoy the story.

And speaking of readers, Far Sector takes place in the universe DC of superheroes. Nevertheless, Campbell y Jeminsin they have managed to create an interesting work that does not need any previous information to understand it and enjoy it. Thus, readers who usually read the sagas of Green Lantern They will enjoy a great story that we could consider the origin of a character that has already begun to appear in other comics. And those who do not usually approach superhero comics but have an interest, can start with this one without any fear as long as they are interested in procedural plots.

We wish to thank the author of this write-up for this amazing material

Far Sector, NK Jemisin and Jamal Campbell’s Green Lantern Noir – Danger Room

) [summary] => ECC recovers in this compilation volume the twelve issues that were originally published of this story that can be read by itself, or understood as the origin of a new Green Lantern. In recent years, the superhero comics that have gone the furthest are those that not only go a little out of the norm ... Read more [atom_content] =>

ECC recovers in this compilation volume the twelve issues that were originally published of this story that can be read by itself, or understood as the origin of a new Green Lantern.

In recent years, the superhero comics that have gone the furthest are those that not only go a little out of the norm but have also been able to include current themes in their development from a prism that makes readers think. And it is that At this point in the story, and taking into account everything that is published each month, better content is increasingly demanded on the pages we read.. And in the specific case of DCwhich has been messing around quite a bit for a few years in terms of administrative decisions, is noticeable for good when they let their authors develop their stories without pressure.

In case of Far Sectorpublished in Spanish by ECC in a single volume, it is quite curious. This story of twelve issues in total appears under the seal DC?s Young Animalco-created by Gerard Way. Yes, the singer and songwriter of My Chemical Romance, who is also a comic book writer and editor. This stamp aims to relaunch characters and stories within the universe DCbut focusing on a more adult age group. Way wanted to create a new version of Green Lantern, in a very special direction, and for this he decided to hire NK Jemisina well-known and award-winning novelist. And she said yes. Together with the very detailed graphic section of Jamal Campbell pops up Far Sectorthe dream of Way came true.

The story of Far Sector it starts with a murder in the Enduring City. The first in five hundred years. The problem? That world has spent generations without suffering any kind of violent death thanks to the control of emotions that the government imposed some time ago. And that means they are not prepared to investigate what has happened. Luckily, the green lanterns are there to protect all corners of space, including that, the furthest sector of planet Earth. Sojourner “Jo” Mullein is still getting used to it to live in a sector where she is the only one who has feelings, where food is more than dangerous for her if she is not careful and where bureaucracy is as tedious as anywhere else. Not counting your adaptation to Green Lantern’s post. Therefore, that first murder will fall into his human hands, with all that this entails.

SectorLejano01

To this must be added that it is the only human, since that sector is inhabited by three species that coexist thanks to the aforementioned control of emotions. If there is no anger, sadness, fear… but no sympathy, love or joy, it seems that as a society it should be quite a walk. However, Mullein has begun to see strange things, emotionally active beings thanks to a new drug that inhibits the control of emotions. In order to save the population of the sector, Mullein must first overcome his past to face his present and thus protect the sector from him.

With these parameters NK Jemisin create a round story where your Green Lantern eShe’s more of an investigator than a conventional superhero. With the perfect mix between noir and science fictionthe script of Jemisin It focuses on the representation of very current problems such as racism, changing races for alien species, abuse of power, hatred and disinformation as political propaganda, among others that we will not specify here so as not to destroy part of the story. Don’t miss out on the action that is expected in this type of comics, and includes battle scenes and development of powers of the protagonist. However, it does so with a procedural narrative typical of the detective genre. Its narrative is quite linear, with a couple of time jumps, in the form of memories, to give more meaning to the story of the protagonist.

SectorLejano02

Jamal Campbell’s graphic sectionwho not only takes care of the drawing but also the color, it is very effective. Striking both in its designs and its colors. With incredible detail in the expressions of the protagonist, and some character designs of the rest of the species that, at times, makes it difficult to think that they are not feeling anything. Sometimes this happens because of the script, but sometimes it’s because the art of Campbell fills them with life. But she doesn’t bother at all, quite the opposite. Furthermore, the edition of ECC It has a section of sketches and character designs in which you can see the use of each of them during the volume. The graphic solutions for the development of the story are quite conventional, including the battles, but both the script and the graphic section make this irrelevant. They do not need large displays for readers to enjoy the story.

And speaking of readers, Far Sector takes place in the universe DC of superheroes. Nevertheless, Campbell y Jeminsin they have managed to create an interesting work that does not need any previous information to understand it and enjoy it. Thus, readers who usually read the sagas of Green Lantern They will enjoy a great story that we could consider the origin of a character that has already begun to appear in other comics. And those who do not usually approach superhero comics but have an interest, can start with this one without any fear as long as they are interested in procedural plots.

We wish to thank the author of this write-up for this amazing material

Far Sector, NK Jemisin and Jamal Campbell’s Green Lantern Noir – Danger Room

[date_timestamp] => 1656169863 ) [5] => Array ( [title] => Love Nature, PBS, Arte Commission ?Evolution Earth? ? Global Bulletin [link] => https://coolnspicy.com/movie-production-companies/love-nature-pbs-arte-commission-evolution-earth-global-bulletin/ [dc] => Array ( [creator] => Sally Scully ) [pubdate] => Sat, 25 Jun 2022 15:09:49 +0000 [category] => Movie Production CompaniesArteBulletinCommissionEarthevolutiongloballovenaturePBS [guid] => https://coolnspicy.com/?p=24732 [description] => COMMISSION Wildlife and nature programmer Love Nature has greenlit five-part natural history series ?Evolution Earth? in co-production with PBS and Art. The series, produced by Passion Planet and shot in extreme locations around the world, is an examination of adaptation stories that illustrate the rapid pace of change happening across Earth, while providing a look ... Read more [content] => Array ( [encoded] =>

COMMISSION

Wildlife and nature programmer Love Nature has greenlit five-part natural history series ?Evolution Earth? in co-production with PBS and Art. The series, produced by Passion Planet and shot in extreme locations around the world, is an examination of adaptation stories that illustrate the rapid pace of change happening across Earth, while providing a look at nature?s ability to thrive.

The series includes five films, each showcasing a different extreme landscape including Earth, Islands, Ice, Heat and Grasslands. It will debut across Love Nature?s branded linear and streaming platforms around the world, PBS in the U.S., Arte in France and Germany and on Sky Nature in the U.K. and Italy. Blue Ant International oversees international licensing opportunities outside of commissioning territories.

David Allen is the director of Passion Planet and series producer alongside Oliver Twinch. James Manfull executive produces the series on behalf of Love Nature. Executive in charge for PBS is VP of multi-platform programming and head of development, Bill Gardner. Executive producer for Arte is Hélène Coldefy, head of factual.

***

Meanwhile, U.K. broadcaster ITV has commissioned a one-off documentary from Spun Gold TV with exclusive access to Camilla Parker Bowlesthe Duchess of Cornwallin her role as guest editor of Country Life magazine to mark her 75th birthday. ?Camilla?s Country Life? (working title, 1×60?), from director Michael Waldman (?Inside the Foreign Office?), accompanies the Duchess as she plans and oversees a special edition during the magazine?s 125th anniversary year, alongside performing her regular royal duties. The producer is Ross Curran and the executive producer is Nick Bullen. It was commissioned for ITV by Jo Clinton-Davis. All3Media International has worldwide distribution rights.

ANIMATION

Leading animation studio Aardman has launched a new teaser from its comedy series of entomology, ?Lloyd of the Flies,? to celebrate Insect Week. The series follows the adventures of Lloyd B Fly, a housefly and the middle child of 453. Lloyd lives with his parents, his little sister PB and their 225 maggot siblings inside a compost bin they call home. In the series, Lloyd is always accompanied by his best and only friend, Abacus Woodlouse, PB, and eccentric tag-along, Cornea Butterfly. Together they explore the strange world beyond the compost bin.

Aardman has also revealed Jamie-Lee O?Donnell (?Derry Girls?) as a new addition to the voice cast. She stars alongside Tom Rosenthal (?Friday Night Dinner?), Alex Lawther (?The End of the F***ing World?), Lauren Patel (?Everybody?s Talking About Jamie?) and Callum Scott Howells (?It?s A Sin?). The 52 x 11? series will premiere on CiTV in September.

FESTIVAL

London?s Soho Media Club will host Be Youa day-long festival of honest discussions about inclusion, diversity, talent and mental health in film and TV and challenge the status quo, on July 14.

Featured speakers include ?Untouchable? director Ursula Macfarlane; Teddy Nygh and Nick Beduco-founders of Fully Focused, a youth-driven and youth-focused production company; director Coky Giedroyc (?Save Me?); ?Ten Percent? director and playwright Jessica Swale; ?You Don?t Know Me? producer and disability campaigner Jules Hussey; and Ace Ruelemotion capture actor, creature bionics. There will be panels on holistic diversity, diversity in post and accessible tech and mental health.

?Soho Media Club meet-ups have attracted a wide and diverse audience from all parts of the industry, at all levels ? from students and runners, to directors, producers, editors, commissioners, CEOs and company owners. It made us realise that people in TV and film want to widen their connections, share their stories and there?s a real momentum to change things for the better. The time is right for the Be You Festival to help move the dial and celebrate the TV industry in all its diversity,? said Jaisica Lapsiwalaco-founder, Soho Media Club.

We wish to thank the author of this short article for this amazing material

Love Nature, PBS, Arte Commission ?Evolution Earth? ? Global Bulletin

) [summary] => COMMISSION Wildlife and nature programmer Love Nature has greenlit five-part natural history series ?Evolution Earth? in co-production with PBS and Art. The series, produced by Passion Planet and shot in extreme locations around the world, is an examination of adaptation stories that illustrate the rapid pace of change happening across Earth, while providing a look ... Read more [atom_content] =>

COMMISSION

Wildlife and nature programmer Love Nature has greenlit five-part natural history series ?Evolution Earth? in co-production with PBS and Art. The series, produced by Passion Planet and shot in extreme locations around the world, is an examination of adaptation stories that illustrate the rapid pace of change happening across Earth, while providing a look at nature?s ability to thrive.

The series includes five films, each showcasing a different extreme landscape including Earth, Islands, Ice, Heat and Grasslands. It will debut across Love Nature?s branded linear and streaming platforms around the world, PBS in the U.S., Arte in France and Germany and on Sky Nature in the U.K. and Italy. Blue Ant International oversees international licensing opportunities outside of commissioning territories.

David Allen is the director of Passion Planet and series producer alongside Oliver Twinch. James Manfull executive produces the series on behalf of Love Nature. Executive in charge for PBS is VP of multi-platform programming and head of development, Bill Gardner. Executive producer for Arte is Hélène Coldefy, head of factual.

***

Meanwhile, U.K. broadcaster ITV has commissioned a one-off documentary from Spun Gold TV with exclusive access to Camilla Parker Bowlesthe Duchess of Cornwallin her role as guest editor of Country Life magazine to mark her 75th birthday. ?Camilla?s Country Life? (working title, 1×60?), from director Michael Waldman (?Inside the Foreign Office?), accompanies the Duchess as she plans and oversees a special edition during the magazine?s 125th anniversary year, alongside performing her regular royal duties. The producer is Ross Curran and the executive producer is Nick Bullen. It was commissioned for ITV by Jo Clinton-Davis. All3Media International has worldwide distribution rights.

ANIMATION

Leading animation studio Aardman has launched a new teaser from its comedy series of entomology, ?Lloyd of the Flies,? to celebrate Insect Week. The series follows the adventures of Lloyd B Fly, a housefly and the middle child of 453. Lloyd lives with his parents, his little sister PB and their 225 maggot siblings inside a compost bin they call home. In the series, Lloyd is always accompanied by his best and only friend, Abacus Woodlouse, PB, and eccentric tag-along, Cornea Butterfly. Together they explore the strange world beyond the compost bin.

Aardman has also revealed Jamie-Lee O?Donnell (?Derry Girls?) as a new addition to the voice cast. She stars alongside Tom Rosenthal (?Friday Night Dinner?), Alex Lawther (?The End of the F***ing World?), Lauren Patel (?Everybody?s Talking About Jamie?) and Callum Scott Howells (?It?s A Sin?). The 52 x 11? series will premiere on CiTV in September.

FESTIVAL

London?s Soho Media Club will host Be Youa day-long festival of honest discussions about inclusion, diversity, talent and mental health in film and TV and challenge the status quo, on July 14.

Featured speakers include ?Untouchable? director Ursula Macfarlane; Teddy Nygh and Nick Beduco-founders of Fully Focused, a youth-driven and youth-focused production company; director Coky Giedroyc (?Save Me?); ?Ten Percent? director and playwright Jessica Swale; ?You Don?t Know Me? producer and disability campaigner Jules Hussey; and Ace Ruelemotion capture actor, creature bionics. There will be panels on holistic diversity, diversity in post and accessible tech and mental health.

?Soho Media Club meet-ups have attracted a wide and diverse audience from all parts of the industry, at all levels ? from students and runners, to directors, producers, editors, commissioners, CEOs and company owners. It made us realise that people in TV and film want to widen their connections, share their stories and there?s a real momentum to change things for the better. The time is right for the Be You Festival to help move the dial and celebrate the TV industry in all its diversity,? said Jaisica Lapsiwalaco-founder, Soho Media Club.

We wish to thank the author of this short article for this amazing material

Love Nature, PBS, Arte Commission ?Evolution Earth? ? Global Bulletin

[date_timestamp] => 1656169789 ) [6] => Array ( [title] => As US obesity epidemic grows, new study shows who is gaining weight over the last decade [link] => https://coolnspicy.com/healthandscience/as-us-obesity-epidemic-grows-new-study-shows-who-is-gaining-weight-over-the-last-decade/ [dc] => Array ( [creator] => Tony Grantly ) [pubdate] => Sat, 25 Jun 2022 14:19:54 +0000 [category] => Health And SciencedecadeepidemicgaininggrowsobesityStudyWeight [guid] => https://coolnspicy.com/?p=24727 [description] => Journal Reference: Larry A. Tucker, Kayla Parker. 10-Year Weight Gain in 13,802 US Adults: The Role of Age, Sex, and Race. Journal of Obesity, 2022; 2022: 1 DOI: 10.1155/2022/7652408 The article, published in the Journal of Obesity, looked at the long-term weight gain of more than 13,800 U.S. adults ? a rare data point unearthed ... Read more [content] => Array ( [encoded] =>

Journal Reference:

  1. Larry A. Tucker, Kayla Parker. 10-Year Weight Gain in 13,802 US Adults: The Role of Age, Sex, and Race. Journal of Obesity, 2022; 2022: 1 DOI: 10.1155/2022/7652408

The article, published in the Journal of Obesity, looked at the long-term weight gain of more than 13,800 U.S. adults ? a rare data point unearthed in obesity research. They found that more than half of American adults in the study gained 5% or more body weight over a 10-year period. What?s more, more than a third of American adults gained 10% or more body weight and almost a fifth gained 20% or more body weight.

?The U.S. obesity epidemic is not slowing down,? said study lead author Larry Tucker, a BYU professor of exercise science. ?Without question, 10-year weight gain is a serious problem within the U.S. adult population.?

Study participants were selected randomly as part of the National Health and Nutrition Examination Survey, an annual survey that examines a nationally representative sample. NHANES is a CDC-sponsored series of studies that began in the early 1960s and became a continuous program in 1999.

Using the NHANES data, the study also found that 10-year weight gain was significantly greater in women than in men, with women gaining about twice as much weight: 12 pounds on average for women compared to 6 pounds for men. Weight gain also differed across races, with Black women experiencing the greatest average weight gain over the 10-year period (19.4 pounds) and Asian men experiencing the least (2.9 pounds).

As far as age goes, the greatest gains in weight were found in young and middle-aged adults; less weight is gained as age increases. According to the data, on average Americans gain the following weight:

If adults gain the average amount of weight during each decade of adult life, they will have gained more than 45 pounds, which would push many of them into the obese category. According to the Department of Health and Human Services and the CDC, 42.4% of U.S. adults are currently obese. That?s up substantially from the 30.5% measured in 2000.

?In roughly 20 years, the prevalence of obesity increased by approximately 40% and severe obesity almost doubled,? Tucker said. ?By knowing who is more likely to become obese, we can help health care providers and public health officials focus more on at-risk individuals.?

We would love to give thanks to the writer of this post for this remarkable content

As US obesity epidemic grows, new study shows who is gaining weight over the last decade

) [summary] => Journal Reference: Larry A. Tucker, Kayla Parker. 10-Year Weight Gain in 13,802 US Adults: The Role of Age, Sex, and Race. Journal of Obesity, 2022; 2022: 1 DOI: 10.1155/2022/7652408 The article, published in the Journal of Obesity, looked at the long-term weight gain of more than 13,800 U.S. adults ? a rare data point unearthed ... Read more [atom_content] =>

Journal Reference:

  1. Larry A. Tucker, Kayla Parker. 10-Year Weight Gain in 13,802 US Adults: The Role of Age, Sex, and Race. Journal of Obesity, 2022; 2022: 1 DOI: 10.1155/2022/7652408

The article, published in the Journal of Obesity, looked at the long-term weight gain of more than 13,800 U.S. adults ? a rare data point unearthed in obesity research. They found that more than half of American adults in the study gained 5% or more body weight over a 10-year period. What?s more, more than a third of American adults gained 10% or more body weight and almost a fifth gained 20% or more body weight.

?The U.S. obesity epidemic is not slowing down,? said study lead author Larry Tucker, a BYU professor of exercise science. ?Without question, 10-year weight gain is a serious problem within the U.S. adult population.?

Study participants were selected randomly as part of the National Health and Nutrition Examination Survey, an annual survey that examines a nationally representative sample. NHANES is a CDC-sponsored series of studies that began in the early 1960s and became a continuous program in 1999.

Using the NHANES data, the study also found that 10-year weight gain was significantly greater in women than in men, with women gaining about twice as much weight: 12 pounds on average for women compared to 6 pounds for men. Weight gain also differed across races, with Black women experiencing the greatest average weight gain over the 10-year period (19.4 pounds) and Asian men experiencing the least (2.9 pounds).

As far as age goes, the greatest gains in weight were found in young and middle-aged adults; less weight is gained as age increases. According to the data, on average Americans gain the following weight:

If adults gain the average amount of weight during each decade of adult life, they will have gained more than 45 pounds, which would push many of them into the obese category. According to the Department of Health and Human Services and the CDC, 42.4% of U.S. adults are currently obese. That?s up substantially from the 30.5% measured in 2000.

?In roughly 20 years, the prevalence of obesity increased by approximately 40% and severe obesity almost doubled,? Tucker said. ?By knowing who is more likely to become obese, we can help health care providers and public health officials focus more on at-risk individuals.?

We would love to give thanks to the writer of this post for this remarkable content

As US obesity epidemic grows, new study shows who is gaining weight over the last decade

[date_timestamp] => 1656166794 ) [7] => Array ( [title] => Tom Hanks: the all-American good guy who stopped playing it safe [link] => https://coolnspicy.com/trending-people/tom-hanks-the-all-american-good-guy-who-stopped-playing-it-safe/ [dc] => Array ( [creator] => Pauline Moonlky ) [pubdate] => Sat, 25 Jun 2022 14:13:22 +0000 [category] => Trending PeopleallAmericanguyHanksPlayingSafestoppedTom [guid] => https://coolnspicy.com/?p=24721 [description] => In performing arts schools and training programs, instructors often say that acting is about making big, decisive choices and committing to them totally. This seems like the best way to make sense of Tom Hanks? outsized supporting turn in the new biopic Elvis as ?Colonel? Tom Parker, Elvis Aaron Presley?s Dutch-born manager and parasitic, gambling-addicted ... Read more [content] => Array ( [encoded] =>

In performing arts schools and training programs, instructors often say that acting is about making big, decisive choices and committing to them totally. This seems like the best way to make sense of Tom Hanks? outsized supporting turn in the new biopic Elvis as ?Colonel? Tom Parker, Elvis Aaron Presley?s Dutch-born manager and parasitic, gambling-addicted svengali. Among the more puzzling choices made by Hanks: speaking in a vinegary twang that?s sometimes regionally indistinct, sometimes a legible fusion of deep south drawl and lyrical Euro-lilt; donning a prosthetic neck that makes him look like he?s liable to yell at Elvis to ?get in my belly?; assuming a lumbering physicality that only grows more pronounced as Colonel Tom prepares to shuffle off his mortal coil in a (probably) metaphorical casino of fate. Having mastered the craft and won all the accolades, he now appears to be motivated primarily by his own amusement, like a video gamer who?s beaten the final boss and moved on to exploring the farthest limits of the virtual world in search of glitches.

As inexplicable as his Colonel Tom may be on a minute-by-minute basis, as a whole, the wild-eyed performance fits squarely within the context of Hanks?s career in its semi-experimental, drastically inconsistent late phase. The last decade has seen one of the planet?s biggest movie stars punctuating stretches of typecast roles with strange and often misbegotten forays into less-familiar territory, to varying degrees of success. He could be getting bored and looking for a novel test of skill, or as an uncharacteristically gruff recent encounter with mobbing fans suggests, he could be developing an edge as he advances through his 60s. Whatever the case, an image forms of a restless ageing expert, torn between excelling in what he?s good at and challenging himself no matter how sparse his success. For someone who?s more than earned the complacency of middle age, his continued unpredictability makes for a cockeyed act of generosity.

Hanks as Colonel Tom Parker in Elvis, Baz Luhrmann?s new biopic. Photograph: Album/Alamy

Up to this point, Hanks?s screen persona has been easy enough to isolate and define, his filmography well-stocked with various types of decent fellas. His splashy TV arrival in Bosom Buddies, the man-boy blockbusters like Splash and The Money Pit (then made literal by Big), the pivot to Oscar-festooned middlebrow prestige, the romcom era ? they?re all united by a foundation of goodness, a red-meat morality that made Hanks impossible to hate even when playing emissary to a faceless corporation bent on flushing out Mom and Pop. With time, he?d graduate from America?s best pal, always ready with a cold beer and pick-me-up speech, to America?s dad, Atticus Finch with comedic timing. In a 2011 cameo as himself on 30 Rock, he?s seen spending his nights singing to himself and knitting in front of a television set to a low, gentle volume.

But his path hooked away from a future of porridge and prune juice in the 2010s, and split into an intriguing network of forks. He hasn?t parted ways with the Hanks we?ve come to cherish, though recent invocations of his good-guy typecasting have taken on fresh inflections. The one-time savior of Private Ryan spent much of the decade upholding the American way of life, whether by brokering peace (as in Bridge of Spies, Captain Phillips and News of the World, the latter taking him to a coarser register), defending the truth (as in The Post), and fighting for individual freedoms against the evils of big government oversight (as in Sully, though he?s more subordinate to director Clint Eastwood?s ideology). The squeaky-cleanest entries come close to parody of this tendency, though such physical embodiments of childhood purity as Walt Disney and Fred Rogers would be ultimately played straight by their attendant scripts.

Hanks as a mutton-chopped gangster in Cloud Atlas.
Hanks as a mutton-chopped gangster in Cloud Atlas. Photograph: Warner Bros/Kobal/Rex/Shutterstock

If Hanks has a one-for-them, one-for-me policy, it?s in terms of mass appeal rather than personal relevance; for each crowd-pleaser that puts him back in his wheelhouse, he?s taken a gig farther off the beaten path that allows him to try out some things he hasn?t done before. As with so many men approaching his autumn years, he?s dabbled in existentialism, from the crisis-driven soul-searching of A Hologram for the King to the funereal legacy-building of Finch (in which his post-apocalyptic survivor must teach a robot to care for the world he won?t inhabit much longer). He went full-on villainous for The Circle, in which he played a big tech creep bent on full transparency through the digital surveillance state, which would?ve been his oeuvre?s most shocking departure if not for Cloud Atlas. Hanks?s noodling-around phase begins here, his six-character tour de force through the time-hopping anthological structure affording him the chance to branch out in a half-dozen different directions at once.

Whether Hanks was effective as a mutton-chopped limey gangster in Cloud Atlas can be argued ad infinitum, though that?s neither here nor there. For a few glittering moments, we can see that the most likable man in show business isn?t all that concerned with being liked, guided by a more flighty, intimate muse than he?s answered before. In the coming months, he?ll star in an American remake of the Swedish comedy A Man Called Ove (if anything like the original, an opportunity to him to don some more heavy-duty facial prosthetics) and link up with Wes Anderson for the first time on the Spain-set Asteroid City. In a career now rolling through its fifth decade, he?s still finding new firsts, easing his chief virtue of charm and ceding its space to curiosity for its own sake. Say what you will about Hanks?s showing in Elvis as Mephistopheles doused in sausage gravy: it?s proof that there?s nothing he won?t, or can?t, do.

We want to thank the writer of this write-up for this awesome material

Tom Hanks: the all-American good guy who stopped playing it safe

) [summary] => In performing arts schools and training programs, instructors often say that acting is about making big, decisive choices and committing to them totally. This seems like the best way to make sense of Tom Hanks? outsized supporting turn in the new biopic Elvis as ?Colonel? Tom Parker, Elvis Aaron Presley?s Dutch-born manager and parasitic, gambling-addicted ... Read more [atom_content] =>

In performing arts schools and training programs, instructors often say that acting is about making big, decisive choices and committing to them totally. This seems like the best way to make sense of Tom Hanks? outsized supporting turn in the new biopic Elvis as ?Colonel? Tom Parker, Elvis Aaron Presley?s Dutch-born manager and parasitic, gambling-addicted svengali. Among the more puzzling choices made by Hanks: speaking in a vinegary twang that?s sometimes regionally indistinct, sometimes a legible fusion of deep south drawl and lyrical Euro-lilt; donning a prosthetic neck that makes him look like he?s liable to yell at Elvis to ?get in my belly?; assuming a lumbering physicality that only grows more pronounced as Colonel Tom prepares to shuffle off his mortal coil in a (probably) metaphorical casino of fate. Having mastered the craft and won all the accolades, he now appears to be motivated primarily by his own amusement, like a video gamer who?s beaten the final boss and moved on to exploring the farthest limits of the virtual world in search of glitches.

As inexplicable as his Colonel Tom may be on a minute-by-minute basis, as a whole, the wild-eyed performance fits squarely within the context of Hanks?s career in its semi-experimental, drastically inconsistent late phase. The last decade has seen one of the planet?s biggest movie stars punctuating stretches of typecast roles with strange and often misbegotten forays into less-familiar territory, to varying degrees of success. He could be getting bored and looking for a novel test of skill, or as an uncharacteristically gruff recent encounter with mobbing fans suggests, he could be developing an edge as he advances through his 60s. Whatever the case, an image forms of a restless ageing expert, torn between excelling in what he?s good at and challenging himself no matter how sparse his success. For someone who?s more than earned the complacency of middle age, his continued unpredictability makes for a cockeyed act of generosity.

Hanks as Colonel Tom Parker in Elvis, Baz Luhrmann?s new biopic. Photograph: Album/Alamy

Up to this point, Hanks?s screen persona has been easy enough to isolate and define, his filmography well-stocked with various types of decent fellas. His splashy TV arrival in Bosom Buddies, the man-boy blockbusters like Splash and The Money Pit (then made literal by Big), the pivot to Oscar-festooned middlebrow prestige, the romcom era ? they?re all united by a foundation of goodness, a red-meat morality that made Hanks impossible to hate even when playing emissary to a faceless corporation bent on flushing out Mom and Pop. With time, he?d graduate from America?s best pal, always ready with a cold beer and pick-me-up speech, to America?s dad, Atticus Finch with comedic timing. In a 2011 cameo as himself on 30 Rock, he?s seen spending his nights singing to himself and knitting in front of a television set to a low, gentle volume.

But his path hooked away from a future of porridge and prune juice in the 2010s, and split into an intriguing network of forks. He hasn?t parted ways with the Hanks we?ve come to cherish, though recent invocations of his good-guy typecasting have taken on fresh inflections. The one-time savior of Private Ryan spent much of the decade upholding the American way of life, whether by brokering peace (as in Bridge of Spies, Captain Phillips and News of the World, the latter taking him to a coarser register), defending the truth (as in The Post), and fighting for individual freedoms against the evils of big government oversight (as in Sully, though he?s more subordinate to director Clint Eastwood?s ideology). The squeaky-cleanest entries come close to parody of this tendency, though such physical embodiments of childhood purity as Walt Disney and Fred Rogers would be ultimately played straight by their attendant scripts.

Hanks as a mutton-chopped gangster in Cloud Atlas.
Hanks as a mutton-chopped gangster in Cloud Atlas. Photograph: Warner Bros/Kobal/Rex/Shutterstock

If Hanks has a one-for-them, one-for-me policy, it?s in terms of mass appeal rather than personal relevance; for each crowd-pleaser that puts him back in his wheelhouse, he?s taken a gig farther off the beaten path that allows him to try out some things he hasn?t done before. As with so many men approaching his autumn years, he?s dabbled in existentialism, from the crisis-driven soul-searching of A Hologram for the King to the funereal legacy-building of Finch (in which his post-apocalyptic survivor must teach a robot to care for the world he won?t inhabit much longer). He went full-on villainous for The Circle, in which he played a big tech creep bent on full transparency through the digital surveillance state, which would?ve been his oeuvre?s most shocking departure if not for Cloud Atlas. Hanks?s noodling-around phase begins here, his six-character tour de force through the time-hopping anthological structure affording him the chance to branch out in a half-dozen different directions at once.

Whether Hanks was effective as a mutton-chopped limey gangster in Cloud Atlas can be argued ad infinitum, though that?s neither here nor there. For a few glittering moments, we can see that the most likable man in show business isn?t all that concerned with being liked, guided by a more flighty, intimate muse than he?s answered before. In the coming months, he?ll star in an American remake of the Swedish comedy A Man Called Ove (if anything like the original, an opportunity to him to don some more heavy-duty facial prosthetics) and link up with Wes Anderson for the first time on the Spain-set Asteroid City. In a career now rolling through its fifth decade, he?s still finding new firsts, easing his chief virtue of charm and ceding its space to curiosity for its own sake. Say what you will about Hanks?s showing in Elvis as Mephistopheles doused in sausage gravy: it?s proof that there?s nothing he won?t, or can?t, do.

We want to thank the writer of this write-up for this awesome material

Tom Hanks: the all-American good guy who stopped playing it safe

[date_timestamp] => 1656166402 ) [8] => Array ( [title] => Environmental factors predict risk of death [link] => https://coolnspicy.com/healthandscience/environmental-factors-predict-risk-of-death/ [dc] => Array ( [creator] => Tony Grantly ) [pubdate] => Sat, 25 Jun 2022 13:03:12 +0000 [category] => Health And SciencedeathenvironmentalFactorspredictRisk [guid] => https://coolnspicy.com/?p=24716 [description] => Journal Reference: Michael B. Hadley, Mahdi Nalini, Samrachana Adhikari, Jackie Szymonifka, Arash Etemadi, Farin Kamangar, Masoud Khoshnia, Tyler McChane, Akram Pourshams, Hossein Poustchi, Sadaf G. Sepanlou, Christian Abnet, Neal D. Freedman, Paolo Boffetta, Reza Malekzadeh, Rajesh Vedanthan. Spatial environmental factors predict cardiovascular and all-cause mortality: Results of the SPACE study. PLOS ONE, 2022; 17 (6): ... Read more [content] => Array ( [encoded] =>

Journal Reference:

  1. Michael B. Hadley, Mahdi Nalini, Samrachana Adhikari, Jackie Szymonifka, Arash Etemadi, Farin Kamangar, Masoud Khoshnia, Tyler McChane, Akram Pourshams, Hossein Poustchi, Sadaf G. Sepanlou, Christian Abnet, Neal D. Freedman, Paolo Boffetta, Reza Malekzadeh, Rajesh Vedanthan. Spatial environmental factors predict cardiovascular and all-cause mortality: Results of the SPACE study. PLOS ONE, 2022; 17 (6): e0269650 DOI: 10.1371/journal.pone.0269650

Led by researchers at NYU Grossman School of Medicine and the Icahn School of Medicine at Mount Sinai, the study showed that exposure to above average levels of outdoor air pollution increased risk of death by 20%, and risk of death from cardiovascular disease by 17%.

Using wood- or kerosene-burning stoves, not properly ventilated through a chimney, to cook food or heat the home also increasd overall risk of death (by 23% and 9%) and cardiovascular death risk (by 36% and 19%). Living far from specialty medical clinics and near busy roads also increased risk of death.

Publishing in the journal PLOS ONE online June 24, the findings come from personal and environmental health data collected from 50,045 mostly poor, rural villagers living in the northeast Golestan region of Iran. All study participants were over age 40 and agreed to have their health monitored during annual visits with researchers dating as far back as 2004.

Researchers say their latest investigation not only identifies environmental factors that pose the greatest risk to heart and overall health, but also adds much-needed scientific evidence from people in low- and middle-income countries. Traditional research on environmental risk factors, the researchers note, has favored urban populations in high-income countries with much greater access to modern health care services.

Compared with those who have easier access to specialized medical services, those living farther away from clinics with catheterization labs able to unblock clogged arteries, for example, were at increased risk of death by 1% for every 10 kilometers (6.2 miles) of distance. In Golestan, most people live more than 50 miles (80 kilometers) away from such modern facilities.

Study results also showed that the one-third of study participants who lived within 500 meters (1,640 feet) of a major roadway had a 13% increased risk of death.

?Our study highlights the role that key environmental factors of indoor/outdoor air pollution, access to modern health services, and proximity to noisy, polluted roadways play in all causes of death and deaths from cardiovascular disease in particular,? says study senior author and cardiologist Rajesh Vedanthan, MD, MPH.

?Our findings help broaden the disease-risk profile beyond age and traditional personal risk factors,? says Vedanthan, an associate professor in the Department of Population Health and the Department of Medicine at NYU Langone Health.

?These results illustrate a new opportunity for health policymakers to reduce the burden of disease in their communities by mitigating the impact of environmental risk factors like air pollution on cardiovascular health,? says study lead author Michael Hadley, MD, a fellow in cardiology and incoming assistant professor of medicine at Mount Sinai.

By contrast, the study showed that other environmental factors included in the analysis ? low neighborhood income levels, increased population density, and too much nighttime light exposure ? were not independent predictors of risk of death, despite previous research in mostly urban settings suggesting otherwise.

For the investigation, researchers analyzed data gathered through December 2018. They then created a predictive model on overall death risk and death risk from cardiovascular disease.

The research team plans to continue its analysis and hopes to apply the predictive model to other countries with the aim of fine-tuning its predictive capacity. They say their new tool could serve as a guide for evaluating the effectiveness of environmental, lifestyle, and personal health changes in reducing mortality rates worldwide.

According to the World Health Organization, one-quarter of all deaths worldwide are now attributable to environmental factors, including poor air and water quality, lack of sanitation, and exposure to toxic chemicals.

Funding for the study was provided by U.S. National Institutes of Health grant R21HL140474.

We would love to say thanks to the author of this post for this awesome material

Environmental factors predict risk of death

) [summary] => Journal Reference: Michael B. Hadley, Mahdi Nalini, Samrachana Adhikari, Jackie Szymonifka, Arash Etemadi, Farin Kamangar, Masoud Khoshnia, Tyler McChane, Akram Pourshams, Hossein Poustchi, Sadaf G. Sepanlou, Christian Abnet, Neal D. Freedman, Paolo Boffetta, Reza Malekzadeh, Rajesh Vedanthan. Spatial environmental factors predict cardiovascular and all-cause mortality: Results of the SPACE study. PLOS ONE, 2022; 17 (6): ... Read more [atom_content] =>

Journal Reference:

  1. Michael B. Hadley, Mahdi Nalini, Samrachana Adhikari, Jackie Szymonifka, Arash Etemadi, Farin Kamangar, Masoud Khoshnia, Tyler McChane, Akram Pourshams, Hossein Poustchi, Sadaf G. Sepanlou, Christian Abnet, Neal D. Freedman, Paolo Boffetta, Reza Malekzadeh, Rajesh Vedanthan. Spatial environmental factors predict cardiovascular and all-cause mortality: Results of the SPACE study. PLOS ONE, 2022; 17 (6): e0269650 DOI: 10.1371/journal.pone.0269650

Led by researchers at NYU Grossman School of Medicine and the Icahn School of Medicine at Mount Sinai, the study showed that exposure to above average levels of outdoor air pollution increased risk of death by 20%, and risk of death from cardiovascular disease by 17%.

Using wood- or kerosene-burning stoves, not properly ventilated through a chimney, to cook food or heat the home also increasd overall risk of death (by 23% and 9%) and cardiovascular death risk (by 36% and 19%). Living far from specialty medical clinics and near busy roads also increased risk of death.

Publishing in the journal PLOS ONE online June 24, the findings come from personal and environmental health data collected from 50,045 mostly poor, rural villagers living in the northeast Golestan region of Iran. All study participants were over age 40 and agreed to have their health monitored during annual visits with researchers dating as far back as 2004.

Researchers say their latest investigation not only identifies environmental factors that pose the greatest risk to heart and overall health, but also adds much-needed scientific evidence from people in low- and middle-income countries. Traditional research on environmental risk factors, the researchers note, has favored urban populations in high-income countries with much greater access to modern health care services.

Compared with those who have easier access to specialized medical services, those living farther away from clinics with catheterization labs able to unblock clogged arteries, for example, were at increased risk of death by 1% for every 10 kilometers (6.2 miles) of distance. In Golestan, most people live more than 50 miles (80 kilometers) away from such modern facilities.

Study results also showed that the one-third of study participants who lived within 500 meters (1,640 feet) of a major roadway had a 13% increased risk of death.

?Our study highlights the role that key environmental factors of indoor/outdoor air pollution, access to modern health services, and proximity to noisy, polluted roadways play in all causes of death and deaths from cardiovascular disease in particular,? says study senior author and cardiologist Rajesh Vedanthan, MD, MPH.

?Our findings help broaden the disease-risk profile beyond age and traditional personal risk factors,? says Vedanthan, an associate professor in the Department of Population Health and the Department of Medicine at NYU Langone Health.

?These results illustrate a new opportunity for health policymakers to reduce the burden of disease in their communities by mitigating the impact of environmental risk factors like air pollution on cardiovascular health,? says study lead author Michael Hadley, MD, a fellow in cardiology and incoming assistant professor of medicine at Mount Sinai.

By contrast, the study showed that other environmental factors included in the analysis ? low neighborhood income levels, increased population density, and too much nighttime light exposure ? were not independent predictors of risk of death, despite previous research in mostly urban settings suggesting otherwise.

For the investigation, researchers analyzed data gathered through December 2018. They then created a predictive model on overall death risk and death risk from cardiovascular disease.

The research team plans to continue its analysis and hopes to apply the predictive model to other countries with the aim of fine-tuning its predictive capacity. They say their new tool could serve as a guide for evaluating the effectiveness of environmental, lifestyle, and personal health changes in reducing mortality rates worldwide.

According to the World Health Organization, one-quarter of all deaths worldwide are now attributable to environmental factors, including poor air and water quality, lack of sanitation, and exposure to toxic chemicals.

Funding for the study was provided by U.S. National Institutes of Health grant R21HL140474.

We would love to say thanks to the author of this post for this awesome material

Environmental factors predict risk of death

[date_timestamp] => 1656162192 ) [9] => Array ( [title] => Flexing the power of a conductive polymer [link] => https://coolnspicy.com/healthandscience/flexing-the-power-of-a-conductive-polymer/ [dc] => Array ( [creator] => Tony Grantly ) [pubdate] => Sat, 25 Jun 2022 11:45:18 +0000 [category] => Health And ScienceconductiveFlexingpolymerpower [guid] => https://coolnspicy.com/?p=24711 [description] => Journal Reference: Tung Nguyen?Dang, Sangmin Chae, Jirat Chatsirisupachai, Hiba Wakidi, Vinich Promarak, Yon Visell, Thuc?Quyen Nguyen. Dual?Mode Organic Electrochemical Transistors Based on Self?Doped Conjugated Polyelectrolytes for Reconfigurable Electronics (Adv. Mater. 23/2022). Advanced Materials, 2022; 34 (23): 2270170 DOI: 10.1002/adma.202270170 ?Organic semiconductors offer several distinct advantages over conventional silicon-based semiconducting devices: they are made from abundantly ... Read more [content] => Array ( [encoded] =>

Journal Reference:

  1. Tung Nguyen?Dang, Sangmin Chae, Jirat Chatsirisupachai, Hiba Wakidi, Vinich Promarak, Yon Visell, Thuc?Quyen Nguyen. Dual?Mode Organic Electrochemical Transistors Based on Self?Doped Conjugated Polyelectrolytes for Reconfigurable Electronics (Adv. Mater. 23/2022). Advanced Materials, 2022; 34 (23): 2270170 DOI: 10.1002/adma.202270170

?Organic semiconductors offer several distinct advantages over conventional silicon-based semiconducting devices: they are made from abundantly available elements, such as carbon, hydrogen and nitrogen; they offer mechanical flexibility and low cost of manufacture; and they can be fabricated easily at scale,? notes UC Santa Barbara engineering professor Yon Visell, part of a group of researchers working with the new materials. ?Perhaps more importantly, the polymers themselves can be crafted using a wide variety of chemistry methods to endow the resulting semiconducting devices with interesting optical and electrical properties. These properties can be designed, tuned or selected in many more ways than can inorganic (e.g., silicon-based) transistors.?

The design flexibility that Visell describes is exemplified in the reconfigurability of the devices reported by UCSB researchers and others in the journal Advanced Materials.

Reconfigurable logic circuits are of particular interest as candidates for post-CMOS electronics, because they make it possible to simplify circuit design while increasing energy efficiency. One recently developed class of carbon-based (as opposed to, say, silicon- or gallium-nitride-based) transistors), called organic electrochemical transistors(OECTs), have been shown to be well-suited for reconfigurable electronics.

In the recent paper, chemistry professorThuc-Quyen Nguyen,who leads the UCSB Center for Polymers and Organic Solids, and co-authors including Visell describe a breakthrough material ? a soft, semiconducting carbon-based polymer ? that can provide unique advantages over the inorganic semiconductors currently found in conventional silicon transistors.

?Reconfigurable organic logic devices are promising candidates for the next generations of efficient computing systems and adaptive electronics,? the researchers write. ?Ideally, such devices would be of simple structure and design, [as well as] power-efficient and compatible with high-throughput microfabrication techniques.?

Conjugating for Conductivity

A conjugated polyelectrolyte, or CPE-K, consists of a central conjugated backbone, with alternating single and double bonds, and multiple charged side chains with ions attached. ?Having conjugated bonds throughout the polymer makes it conductive, because the delocalized electrons have high mobility across the length of the polymer,? explains lead author Tung Nguyen-Dang, a postdoctoral researcher in Nguyen?s lab who is co-advised by Visell. ?You are marrying two classic materials, the polymer and the semiconductor, in this molecular design.?

Artificial intelligence (AI) played a role in developing the material. ?You can proceed by trial and error to make a material,? Nguyen says. ?You can make a whole bunch of them and hope for the best, and maybe one out of twenty works or has interesting properties; however, we worked with a professor at California State Northridge, Gang Lu, who used AI to select building blocks and do calculations to get a rough idea of how to proceed, given the energy level and properties we were aiming for.?

Figuring out Reconfigurability

One key benefit of CPE-K is that it enables reconfigurable (?dual-mode?) logic gates, meaning they can be switched on the fly to operate in either depletion mode or accumulation mode, simply by adjusting the voltage at the gate. In depletion mode, current flowing through the active material between the drain and the source is initially high, before application of any gate voltage (a.k.a. the ON state). When the gate voltage is applied, the current drops and the transistor is turned to an OFF state. Accumulation mode is the opposite ? without gate voltage, the transistor is in an OFF position, and applying a gate voltage yields higher current, switching the device to an ON state.

?Conventional electronic logic gates, which are the building blocks for all digital circuits found in computers or smart phones, are hardware that do only the one job they are designed for,? says Nguyen. ?For instance, an AND gate has two inputs and one output, and if the inputs applied to it are all 1, then the output will be 1. Similarly, a NOR gate also has two inputs and one output, but if all of the inputs applied to it are 1, then the output will be 0. Electronic gates are implemented using transistors, and reconfiguring them (such as changing from an AND gate to a NOR gate) requires invasive modification, such as dismantling, which is usually too complicated to be practical.

?Reconfigurable gates, like the one we show, can behave as both types of logic gates, switching from AND to NOR and vice versa by changing only the gate voltage,? she continues. ?Currently in electronics, functionality is defined by structure, but in our device you can change the behavior and make it something else just by changing the voltage applied to it. If we scale up this invention from a single gate to much more complex circuits consisting of many such reconfigurable gates, we can envision a powerful piece of hardware that can be programmed with many more functionalities than conventional ones having the same number of transistors.?

Another advantage to CPE-K-based OECTs: they can be operated at very low voltages, making them suitable for use in personal electronics. That, combined with its flexibility and bio-compatibility, make the material a likely candidate for implanted biosensors, wearable devices and neuromorphic computing systems in which OECTs might serve as artificial synapses or non-volatile memories.

?Our colleague is making devices that can monitor the drop of glucose level in the brain that occurs just before a seizure,? Nguyen explains of a collaborator at the University of Cambridge in England. ?And after detection, another device ? a microfluidic device ? will deliver a drug locally to stop the process before it happens.?

Devices made from CPE-K feature concurrent doping and de-doping depending on the type of ions, according to Nguyen. ?You make the device and put it in a liquid electrolyte ? sodium chloride [i.e., table salt] dissolved in water,? she says. ?You can then drive the sodium to migrate into the CPE-K active layer by applying a positive voltage at the gate. Alternatively, you can change the polarity of the gate voltage and drive chloride to migrate to the active layer. Each scenario produces a different type of ion injection, and those different ions are what allow us to change the modes of device operation.?

Self-doping also simplifies the manufacturing process by removing the extra step of adding dopants. ?A lot of times when you add a dopant, it is not evenly distributed throughout the volume of the material,? Nguyen says. ?The organic doping materials tend to cluster together instead of dispersing. But because our material doesn?t need that step, you don?t run into the issue of uneven dopant distribution. You also avoid the whole process of optimizing the dopant and determining the right mix and proportions, all of which add steps and complicate processing.?

The team also developed a physics model for the device that explains its working mechanism and correctly predicts its behavior in both operation modes, thus demonstrating that the device is doing what it seems to be doing.

Visell concludes, ?This remarkable new transistor technology ideally exemplifies the surprising electronic and computing functionalities that are being enabled through convergent research in chemistry, physics, materials and electrical engineering.?

We wish to thank the writer of this article for this outstanding content

Flexing the power of a conductive polymer

) [summary] => Journal Reference: Tung Nguyen?Dang, Sangmin Chae, Jirat Chatsirisupachai, Hiba Wakidi, Vinich Promarak, Yon Visell, Thuc?Quyen Nguyen. Dual?Mode Organic Electrochemical Transistors Based on Self?Doped Conjugated Polyelectrolytes for Reconfigurable Electronics (Adv. Mater. 23/2022). Advanced Materials, 2022; 34 (23): 2270170 DOI: 10.1002/adma.202270170 ?Organic semiconductors offer several distinct advantages over conventional silicon-based semiconducting devices: they are made from abundantly ... Read more [atom_content] =>

Journal Reference:

  1. Tung Nguyen?Dang, Sangmin Chae, Jirat Chatsirisupachai, Hiba Wakidi, Vinich Promarak, Yon Visell, Thuc?Quyen Nguyen. Dual?Mode Organic Electrochemical Transistors Based on Self?Doped Conjugated Polyelectrolytes for Reconfigurable Electronics (Adv. Mater. 23/2022). Advanced Materials, 2022; 34 (23): 2270170 DOI: 10.1002/adma.202270170

?Organic semiconductors offer several distinct advantages over conventional silicon-based semiconducting devices: they are made from abundantly available elements, such as carbon, hydrogen and nitrogen; they offer mechanical flexibility and low cost of manufacture; and they can be fabricated easily at scale,? notes UC Santa Barbara engineering professor Yon Visell, part of a group of researchers working with the new materials. ?Perhaps more importantly, the polymers themselves can be crafted using a wide variety of chemistry methods to endow the resulting semiconducting devices with interesting optical and electrical properties. These properties can be designed, tuned or selected in many more ways than can inorganic (e.g., silicon-based) transistors.?

The design flexibility that Visell describes is exemplified in the reconfigurability of the devices reported by UCSB researchers and others in the journal Advanced Materials.

Reconfigurable logic circuits are of particular interest as candidates for post-CMOS electronics, because they make it possible to simplify circuit design while increasing energy efficiency. One recently developed class of carbon-based (as opposed to, say, silicon- or gallium-nitride-based) transistors), called organic electrochemical transistors(OECTs), have been shown to be well-suited for reconfigurable electronics.

In the recent paper, chemistry professorThuc-Quyen Nguyen,who leads the UCSB Center for Polymers and Organic Solids, and co-authors including Visell describe a breakthrough material ? a soft, semiconducting carbon-based polymer ? that can provide unique advantages over the inorganic semiconductors currently found in conventional silicon transistors.

?Reconfigurable organic logic devices are promising candidates for the next generations of efficient computing systems and adaptive electronics,? the researchers write. ?Ideally, such devices would be of simple structure and design, [as well as] power-efficient and compatible with high-throughput microfabrication techniques.?

Conjugating for Conductivity

A conjugated polyelectrolyte, or CPE-K, consists of a central conjugated backbone, with alternating single and double bonds, and multiple charged side chains with ions attached. ?Having conjugated bonds throughout the polymer makes it conductive, because the delocalized electrons have high mobility across the length of the polymer,? explains lead author Tung Nguyen-Dang, a postdoctoral researcher in Nguyen?s lab who is co-advised by Visell. ?You are marrying two classic materials, the polymer and the semiconductor, in this molecular design.?

Artificial intelligence (AI) played a role in developing the material. ?You can proceed by trial and error to make a material,? Nguyen says. ?You can make a whole bunch of them and hope for the best, and maybe one out of twenty works or has interesting properties; however, we worked with a professor at California State Northridge, Gang Lu, who used AI to select building blocks and do calculations to get a rough idea of how to proceed, given the energy level and properties we were aiming for.?

Figuring out Reconfigurability

One key benefit of CPE-K is that it enables reconfigurable (?dual-mode?) logic gates, meaning they can be switched on the fly to operate in either depletion mode or accumulation mode, simply by adjusting the voltage at the gate. In depletion mode, current flowing through the active material between the drain and the source is initially high, before application of any gate voltage (a.k.a. the ON state). When the gate voltage is applied, the current drops and the transistor is turned to an OFF state. Accumulation mode is the opposite ? without gate voltage, the transistor is in an OFF position, and applying a gate voltage yields higher current, switching the device to an ON state.

?Conventional electronic logic gates, which are the building blocks for all digital circuits found in computers or smart phones, are hardware that do only the one job they are designed for,? says Nguyen. ?For instance, an AND gate has two inputs and one output, and if the inputs applied to it are all 1, then the output will be 1. Similarly, a NOR gate also has two inputs and one output, but if all of the inputs applied to it are 1, then the output will be 0. Electronic gates are implemented using transistors, and reconfiguring them (such as changing from an AND gate to a NOR gate) requires invasive modification, such as dismantling, which is usually too complicated to be practical.

?Reconfigurable gates, like the one we show, can behave as both types of logic gates, switching from AND to NOR and vice versa by changing only the gate voltage,? she continues. ?Currently in electronics, functionality is defined by structure, but in our device you can change the behavior and make it something else just by changing the voltage applied to it. If we scale up this invention from a single gate to much more complex circuits consisting of many such reconfigurable gates, we can envision a powerful piece of hardware that can be programmed with many more functionalities than conventional ones having the same number of transistors.?

Another advantage to CPE-K-based OECTs: they can be operated at very low voltages, making them suitable for use in personal electronics. That, combined with its flexibility and bio-compatibility, make the material a likely candidate for implanted biosensors, wearable devices and neuromorphic computing systems in which OECTs might serve as artificial synapses or non-volatile memories.

?Our colleague is making devices that can monitor the drop of glucose level in the brain that occurs just before a seizure,? Nguyen explains of a collaborator at the University of Cambridge in England. ?And after detection, another device ? a microfluidic device ? will deliver a drug locally to stop the process before it happens.?

Devices made from CPE-K feature concurrent doping and de-doping depending on the type of ions, according to Nguyen. ?You make the device and put it in a liquid electrolyte ? sodium chloride [i.e., table salt] dissolved in water,? she says. ?You can then drive the sodium to migrate into the CPE-K active layer by applying a positive voltage at the gate. Alternatively, you can change the polarity of the gate voltage and drive chloride to migrate to the active layer. Each scenario produces a different type of ion injection, and those different ions are what allow us to change the modes of device operation.?

Self-doping also simplifies the manufacturing process by removing the extra step of adding dopants. ?A lot of times when you add a dopant, it is not evenly distributed throughout the volume of the material,? Nguyen says. ?The organic doping materials tend to cluster together instead of dispersing. But because our material doesn?t need that step, you don?t run into the issue of uneven dopant distribution. You also avoid the whole process of optimizing the dopant and determining the right mix and proportions, all of which add steps and complicate processing.?

The team also developed a physics model for the device that explains its working mechanism and correctly predicts its behavior in both operation modes, thus demonstrating that the device is doing what it seems to be doing.

Visell concludes, ?This remarkable new transistor technology ideally exemplifies the surprising electronic and computing functionalities that are being enabled through convergent research in chemistry, physics, materials and electrical engineering.?

We wish to thank the writer of this article for this outstanding content

Flexing the power of a conductive polymer

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